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    GlossaryAdalimumab (TNF inhibitor)

    biologic drug that inhibits TNF to reduce inflammation

    Adalimumab, also known by the brand name Humira, is a biologic medication that works by inhibiting tumor necrosis factor (TNF), a substance in the body that causes inflammation. It is commonly used to treat autoimmune conditions such as rheumatoid arthritis, psoriasis, and Crohn's disease by reducing inflammation and altering the immune response.

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      community The MPB itch aka DHT itch is very real.

      in Chat  9 upvotes 2 years ago
      Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 8 months ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community Why hasn’t anyone made a "DHT sponge" biologic yet???

      in Research/Science  45 upvotes 3 weeks ago
      The conversation discusses the potential for developing a biologic "DHT sponge" to neutralize DHT in the bloodstream as a treatment for hair loss, suggesting it could be more targeted and have fewer side effects than current treatments like finasteride and dutasteride. Concerns include the complexity, cost, and potential side effects of such a treatment, as well as skepticism about its feasibility and market interest.

      community Finasteride does deplete important nuero-active steroids

      in Research/Science  9 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Dutasteride actually has different half lives depending on dose

      in Research/Science  37 upvotes 10 months ago
      Dutasteride's half-life varies with dosage, and lower doses can be effective with fewer side effects compared to finasteride. Some users report different side effects with dutasteride and finasteride, and extreme dosages of dutasteride are unnecessary and potentially harmful.