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GlossaryTh1 cytokines

signaling proteins produced by Type 1 helper T cells

Th1 cytokines are signaling proteins produced by a type of immune cell called Type 1 helper T cells (Th1 cells). These cytokines, such as interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α), play a crucial role in activating and directing other immune cells to fight off intracellular pathogens like viruses and certain bacteria. They are also involved in inflammatory responses, which can be relevant in conditions like autoimmune diseases and alopecia areata.

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research Fzd2 Controls Multiple Aspects of Epidermal Development Through Distinct Signaling Mechanisms

1 citations, April 2018 in “Journal of Investigative Dermatology”

Fzd2 is important for skin and hair development through various signaling ways.

research The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications

37 citations, December 2021 in “Cells”

Alopecia areata severity and treatment response are linked to specific cytokine levels.

research Decreased IL-10 Producing Regulatory B Cells in Patients With Alopecia Areata

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

People with alopecia areata have fewer IL-10 producing immune cells, which might contribute to the condition.

Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

research Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal?

June 2022 in “Frontiers in Immunology”

Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.

research A Review on Nanoparticle-Based Herbal Remedies for the Management of Alopecia

January 2020 in “Der Pharmacia Lettre”

Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.

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community When someone posts a scalp tension theory

in Satire 264 upvotes 3 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.