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GlossaryInterleukin-17

protein that promotes inflammation in immune responses

Interleukin-17 (IL-17) is a type of protein known as a cytokine that plays a crucial role in the body's immune response by promoting inflammation. It is produced by a subset of T cells called Th17 cells and is involved in defending against infections, but excessive IL-17 activity is also linked to autoimmune diseases, such as psoriasis and rheumatoid arthritis.

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research The many faces of interleukin-17 in inflammatory skin diseases

77 citations , August 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

IL-17 is a key target for treating inflammatory skin diseases, especially psoriasis.

research Generalized hypertrichosis associated with the use of interleukin 17 blockers in 2 patients with psoriasis

3 citations , July 2020 in “JAAD Case Reports”

Two patients with psoriasis grew extra hair after using certain psoriasis medications.

research Repigmentation and new growth of hairs after anti–interleukin-17 therapy with secukinumab for psoriasis

12 citations , June 2018 in “JAAD Case Reports”

A man's gray hair got darker and thicker after using a psoriasis drug.

research Serum Interleukin 17 in Patients with Pattern Hair Loss

June 2023 in “Benha Journal of Applied Sciences”

Targeting IL-17 could help treat pattern hair loss.

research Serum Level of Interleukin 17 in Alopecia Areata Patients and Its Relation with the Severity of the Disease: a Case Control Study

October 2021 in “QJM: An International Journal of Medicine”

People with severe hair loss have higher levels of a protein called interleukin 17 in their blood.

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community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.