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GlossaryInterleukin-23

protein that promotes inflammation and regulates immune responses

Interleukin-23 (IL-23) is a type of cytokine, which is a protein that plays a crucial role in the immune system by promoting inflammation and helping to regulate the body's defense against infections. It is particularly important in the development and maintenance of certain autoimmune diseases, such as psoriasis and inflammatory bowel disease, by influencing the activity of specific immune cells called T-helper 17 (Th17) cells.

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research Recalcitrant Lichen Planopilaris and Frontal Fibrosing Alopecia Responding to Tildrakizumab

10 citations , May 2020 in “Dermatologic therapy”

Tildrakizumab significantly improved recalcitrant lichen planopilaris and frontal fibrosing alopecia.

research The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications

37 citations , December 2021 in “Cells”

Alopecia areata severity and treatment response are linked to specific cytokine levels.

research Editors' Picks

January 2012 in “Journal of Investigative Dermatology”

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

research Treatment of Chronic Alopecia Areata With Tildrakizumab: An Open-Label Pilot Study

3 citations , March 2020 in “International Journal of Dermatology”

Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.

Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity

research Alopecia Areata Is Characterized by Dysregulation in Systemic Type 17 and Type 2 Cytokines, Which May Contribute to Disease-Associated Psychological Morbidity

57 citations , April 2019 in “British journal of dermatology/British journal of dermatology, Supplement”

Alopecia areata involves immune system imbalances that may lead to depression and anxiety.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 15 upvotes 1 year ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 444 upvotes 4 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.