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    Glossary Interleukin-23

    protein that promotes inflammation and regulates immune responses

    Interleukin-23 (IL-23) is a type of cytokine, which is a protein that plays a crucial role in the immune system by promoting inflammation and helping to regulate the body's defense against infections. It is particularly important in the development and maintenance of certain autoimmune diseases, such as psoriasis and inflammatory bowel disease, by influencing the activity of specific immune cells called T-helper 17 (Th17) cells.

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    1. Generalized hypertrichosis associated with the use of interleukin 17 blockers in 2 patients with psoriasis JAAD Case Reports · 2020 · 3 citations
    2. Association of Serum IL-23 and IL-17 Levels with Alopecia Areata AL-QADISIYAH MEDICAL JOURNAL · 2025
    3. Association of Serum IL-23 and IL-17 Levels with Alopecia Areata AL-QADISIYAH MEDICAL JOURNAL · 2025
    4. Interleukins gene polymorphism in alopecia areata patients: a systematic review 2025 · 1 citations
    5. Dandruff Is a Low‐Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin‐17‐Producing T Cells, and N‐Acyl Ethanolamines Immunity Inflammation and Disease · 2026
    6. Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity 2019 · 57 citations
    7. Autoimmunity and autoimmune co-morbidities in psoriasis Immunology · 2018 · 49 citations
    8. The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications Cells · 2021 · 37 citations
    9. Recalcitrant lichen planopilaris and frontal fibrosing alopecia responding to tildrakizumab Dermatologic therapy · 2020 · 10 citations
    10. Treatment of chronic alopecia areata with tildrakizumab: an open‐label pilot study International Journal of Dermatology · 2020 · 3 citations
    11. Inheritance-Specific Dysregulation of Th1- and Th17-Associated Cytokines in Alopecia Areata Biomolecules · 2023 · 1 citations
    12. Biologic Therapies and Small-Molecule Inhibitors for Dissecting Cellulitis of the Scalp: A Systematic Review Dermatology and Therapy · 2026
    13. Dissecting Cellulitis of the Scalp: Linking Pathogenesis to Therapy Biomedicines · 2026
    14. Comparative evaluation of cytokine profiles in pediatric alopecia areata patients considering concomitant atopic diseases: An observational cohort cross-sectional study Kuban Scientific Medical Bulletin · 2025
    15. Periplaneta americana extract (L.) promotes hair regrowth in Alopecia areata mice by reducing inflammation and modulating skin microbiota Frontiers in Pharmacology · 2025
    16. Editors' Picks Journal of Investigative Dermatology · 2012
    17. 224 Humoral immune response to COVID-19 vaccination in psoriasis patients on biologic therapy is impaired compared to healthy controls 2023
    18. Precision Dermatology: A Review of Molecular Biomarkers and Personalized Therapies Current issues in molecular biology · 2024
    19. 42905 Role of regulatory T and T-helper 17 cells in patients with acute diffuse and total alopecia Journal of the American Academy of Dermatology · 2023
    20. The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner Experimental Dermatology · 2025
    21. Updated Treatment for Acne: Targeted Therapy Based on Pathogenesis Dermatology and Therapy · 2021 · 78 citations
    22. An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice International journal of toxicology · 2015 · 36 citations
    23. Modeling cell–cell communication for immune systems across space and time Current Opinion in Systems Biology · 2019 · 20 citations
    24. Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions F1000Research · 2015 · 15 citations
    25. Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata BBA clinical · 2016 · 12 citations
    26. Antroquinonol Exerts Immunosuppressive Effect on CD8<sup>+</sup> T Cell Proliferation and Activation to Resist Depigmentation Induced by H<sub>2</sub>O<sub>2</sub> Oxidative medicine and cellular longevity · 2017 · 11 citations
    27. Impaired responses of peripheral blood mononuclear cells to T-cell stimulants in alopecia areata patients with a poor response to topical immunotherapy 2008 · 4 citations
    28. RETRACTED: Explore the genetic exposure to alopecia areata Skin Research and Technology · 2024 · 2 citations
    29. Particulate matter exposure induces maternal scalp hair loss after birth in C57/B6 mouse via alteration of inflammatory and apoptotic pathways Frontiers in Endocrinology · 2026
    30. Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology International Journal of Molecular Sciences · 2025