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GlossaryInterleukin-10

regulates immune response by reducing inflammation

Interleukin-10 (IL-10) is a cytokine, a type of protein important for regulating the immune system. It plays a crucial role in limiting inflammation by suppressing the activity of immune cells that can cause tissue damage. This makes IL-10 significant in conditions like autoimmune diseases and chronic inflammation, where the immune system needs to be carefully controlled.

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Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice

research Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice

4 citations, July 2013 in “Journal of Dermatological Science”

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

research Regularities of Change Concentrations of Interleukin-17A, Interleukin-2, and Interleukin-10 in the Blood of People with Alopecia Areata Before and After Treatment with Platelet-Rich Plasma

September 2021 in “Ukraïnsʹkij žurnal medicini, bìologìï ta sportu”

PRP treatment reduces inflammation and increases interleukin-10 in alopecia areata patients.

research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population

101 citations, July 1998 in “Journal of Investigative Dermatology”

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

research Evaluation of Serum Levels of IL-6, IL-10, and TNF-a in Alopecia Areata Patients: A Systematic Review and Meta-Analysis

6 citations, October 2021 in “Biomedical Research and Therapy”

Alopecia areata patients have higher levels of IL-6 and TNF-α.

research Decreased IL-10 Producing Regulatory B Cells in Patients With Alopecia Areata

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

People with alopecia areata have fewer IL-10 producing immune cells, which might contribute to the condition.

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community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 6 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.