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    Glossary Interleukin-17

    protein that promotes inflammation in immune responses

    Interleukin-17 (IL-17) is a type of protein known as a cytokine that plays a crucial role in the body's immune response by promoting inflammation. It is produced by a subset of T cells called Th17 cells and is involved in defending against infections, but excessive IL-17 activity is also linked to autoimmune diseases, such as psoriasis and rheumatoid arthritis.

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    1. The many faces of interleukin-17 in inflammatory skin diseases 2016 · 77 citations
    2. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    3. Alopecia Diffusa while Using Interleukin-17 Inhibitors against Psoriasis Vulgaris Case Reports in Dermatology · 2019 · 20 citations
    4. Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata 2021 · 14 citations
    5. <i>Trichophyton tonsurans</i>‐induced kerion celsi with decreased defensin expression and paradoxically increased interleukin‐17A production The Journal of Dermatology · 2019 · 7 citations
    6. Predominant expression of interleukin (IL)‐17 in chronic alopecia areata compared to IFN‐γ in pathogenic Th17 cells, tissue‐resident memory T cells and natural killer cells JEADV Clinical Practice · 2023 · 3 citations
    7. Generalized hypertrichosis associated with the use of interleukin 17 blockers in 2 patients with psoriasis JAAD Case Reports · 2020 · 3 citations
    8. Increased expression of psoriasin (S100A7) and interleukin 17 (IL-17) in lesional skin in lichen planopilaris Advances in Dermatology and Allergology · 2024 · 2 citations
    9. Interleukin 17 Expression in Psoriatic Skin Lesions before and after Treatment with Platelet Rich Plasma (PrP) 2018 · 2 citations
    10. Dandruff Is a Low‐Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin‐17‐Producing T Cells, and N‐Acyl Ethanolamines Immunity Inflammation and Disease · 2026
    11. Evaluation of Serum Toll-Like Receptor 4, Interferon Gamma, and Interleukin-17 Levels in Iraqi Patients with Alopecia Areata European journal of ecology, biology and agriculture. · 2026
    12. Correlation of immunological variables of interleukin-17 and heat shock protein-70 in ethnic women with polycystic ovary syndrome South Eastern European Journal of Public Health · 2024
    13. Correlation of Immunological Variables of Interleukin-17 and Heat Shock Protein-70 In Ethnic Women with Polycystic Ovary Syndrome South Eastern European Journal of Public Health · 2024
    14. Serum Level of Interleukin 17 in Alopecia Areata Patients and Its Relation with the Severity of the Disease: a Case Control Study QJM: An International Journal of Medicine · 2021
    15. Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi 2016
    16. Assessment of Interleukin-17A and Interleukin-2 Serum Levels in Patients with Alopecia Areata Kufa Medical journal · 2024
    17. Serum Interleukin 17 as a Marker for Alopecia Areata Severity: A Case-Control Study The Egyptian Journal of Hospital Medicine · 2023
    18. Increased serum interleukin-17A levels correlate with disease severity and poor prognostic factors in patients with alopecia areata Dermatology Reports · 2021
    19. Regularities of Change Concentrations of Interleukin-17A, Interleukin-2 and Interleukin-10 in the Blood of People with Alopecia Areata before and after Treatment with Platelet-Rich Plasma Ukraïnsʹkij žurnal medicini, bìologìï ta sportu · 2021
    20. Repigmentation and new growth of hairs after anti–interleukin-17 therapy with secukinumab for psoriasis JAAD Case Reports · 2018 · 12 citations
    21. Serum Interleukin 17 in Patients with Pattern Hair Loss Benha Journal of Applied Sciences · 2023
    22. Detection of Serum Levels of Interleukins-17, 21, 6 and Tumor Necrosis Factor-α in Patients with Patchy Alopecia Areata and Their Association with Disease Severity Diseases · 2025
    23. T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities 2018 · 66 citations
    24. Imbalance of T‐helper 17 and regulatory T cells in patients with alopecia areata The Journal of Dermatology · 2015 · 62 citations
    25. Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity 2019 · 57 citations
    26. Local IL-17 orchestrates skin aging bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    27. Association of Serum IL-23 and IL-17 Levels with Alopecia Areata AL-QADISIYAH MEDICAL JOURNAL · 2025
    28. Association of Serum IL-23 and IL-17 Levels with Alopecia Areata AL-QADISIYAH MEDICAL JOURNAL · 2025
    29. 42905 Role of regulatory T and T-helper 17 cells in patients with acute diffuse and total alopecia Journal of the American Academy of Dermatology · 2023
    30. 068 Pathogenic Th17 cells, CD8+CD69+CD49a- tissue-resident memory T cells and common γ chain receptor + natural killer cells express more IL-17, compared to IFN-γ, under the foxp3+ memory regulatory T cells-depleted microenvironment in patients with chronic alopecia areata Journal of Investigative Dermatology · 2023