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    Glossary Th17 Cytokines

    signaling proteins from T helper 17 cells that promote inflammation

    Th17 cytokines are signaling proteins produced by a specific subset of immune cells known as T helper 17 (Th17) cells. These cytokines play a crucial role in the body's defense against bacterial and fungal infections, as well as in the development of inflammatory and autoimmune diseases. They help coordinate the immune response by promoting inflammation, which can be beneficial in fighting infections but may also contribute to conditions like psoriasis and rheumatoid arthritis.

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    1. The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications Cells · 2021 · 37 citations
    2. Inheritance-Specific Dysregulation of Th1- and Th17-Associated Cytokines in Alopecia Areata Biomolecules · 2023 · 1 citations
    3. A new TH17 cytokine in hidradenitis suppurativa: antimicrobial and pro-inflammatory role of IL-26 2020
    4. Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing 2015 · 176 citations
    5. Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal? Frontiers in Immunology · 2022
    6. Decreased CD200R expression on monocyte-derived macrophages correlates with Th17/Treg imbalance and disease activity in rheumatoid arthritis patients Inflammation Research · 2014 · 31 citations
    7. Healthy individuals genetically at-risk for the development of Pemphigus vulgaris or Alopecia areata share disease-like cytokine dysregulation Frontiers in Immunology · 2025 · 1 citations
    8. Olink proteomics analysis of scalp psoriasis reveals a cytokine storm inflammatory mainly related to bacterial-derived antigens 2025
    9. Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases 2017 · 25 citations
    10. The effect of 5-α reductase inhibitor on Th1, Th2, and Th17 cell-related inflammatory response in BPH World Journal of Urology · 2023 · 1 citations
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