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    Glossary Th2 cytokines

    regulate immune responses, especially in allergies and parasitic infections

    Th2 cytokines are signaling proteins produced by Type 2 helper T cells (Th2 cells) that play a crucial role in the immune system. They help regulate immune responses, particularly by promoting the production of antibodies and combating extracellular parasites like helminths. Th2 cytokines, such as IL-4, IL-5, and IL-13, are also involved in allergic reactions and can contribute to conditions like asthma and eczema.

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    1. The Role of Serum Th1, Th2, and Th17 Cytokines in Patients with Alopecia Areata: Clinical Implications Cells · 2021 · 37 citations
    2. Novel Quinazoline Derivative Induces Differentiation of Keratinocytes and Enhances Skin Barrier Functions against Th2 Cytokine-Mediated Signaling Molecules · 2023 · 2 citations
    3. Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing 2015 · 176 citations
    4. Influence of Gushen Shengfa Pills Combined Wuling Capsules on Th1/Th2 Cytokines in Patients with Alopecia Areata Disease 2015
    5. Alarmin Cytokines as Central Regulators of Cutaneous Immunity Frontiers in Immunology · 2022 · 51 citations
    6. Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata Allergy · 2022 · 15 citations
    7. Case Report: Successful Treatment of Alopecia Universalis With Tofacitinib and Increased Cytokine Levels: Normal Therapeutic Reaction or Danger Signal? Frontiers in Immunology · 2022
    8. Cytokine profiling of alopecia areata phenotypic subsets Journal of the American Academy of Dermatology · 2005
    9. 1315 An Integrated model of alopecia areata biomarkers highlights both Th1/Th2 upregulation, with stronger correlations between Th2 activation and disease severity Journal of Investigative Dermatology · 2018
    10. Cytokine Targeted Therapeutics for Alopecia Areata: Lessons from Atopic Dermatitis and Other Inflammatory Skin Diseases 2017 · 25 citations
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