Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature
January 2012
in “
Dermatology
”
Studysummary In this study, only 1 out of 5 patients with anti-TNF-α induced psoriasiform eruptions showed good response to topical treatment, while systemic therapy and discontinuation of anti-TNF-α may prevent scarring alopecia in severe cases.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The document reported on five cases of psoriasiform eruptions with severe scalp involvement and alopecia induced by anti-TNF-alpha therapy. The study highlighted the adverse effects of anti-TNF-alpha treatments, which are commonly used for conditions like rheumatoid arthritis and Crohn's disease. The patients experienced significant hair loss and scalp issues, which were notable side effects. The review of the literature suggested that while these reactions were rare, they were important for clinicians to recognize and manage appropriately.
