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Glossary Scalp Involvement

presence of a medical condition affecting the scalp

Scalp involvement refers to the presence of a medical condition or disease affecting the scalp. This can include symptoms like redness, itching, scaling, or hair loss, and is often seen in conditions such as psoriasis, seborrheic dermatitis, or alopecia. For professionals, it indicates that the pathology extends to the scalp, necessitating targeted treatment or further diagnostic evaluation.

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Research

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research Anti-TNF-Alpha Induced Psoriasiform Eruptions with Severe Scalp Involvement and Alopecia: Report of Five Cases and Review of the Literature

49 citations , January 2012 in “Dermatology”

In this study, only 1 out of 5 patients with anti-TNF-α induced psoriasiform eruptions showed good response to topical treatment, while systemic therapy and discontinuation of anti-TNF-α may prevent scarring alopecia in severe cases.

research Scalp involvement in pemphigus: a prognostic marker

10 citations , November 2017 in “Advances in Dermatology and Allergology”

This study found that scalp involvement in pemphigus is linked to greater disease severity and longer times to achieve both clinical and serological remission, suggesting it may require more aggressive treatment.

research Associations Between Skin Microbiome and Metabolome in the Pathogenesis of Atopic Dermatitis Patients With Scalp Involvement

3 citations , January 2024 in “Allergy Asthma and Immunology Research”

This study explored the associations between the skin microbiome and metabolome in groups LS, NL, and HC, suggesting potential new pathways for understanding scalp involvement in AD patients, which could improve management strategies.

research Scalp Involvement in Primary Cutaneous Lymphomas—An Update on Clinical Presentation, Diagnostics, and Management

May 2025 in “Cancers”

This review analyzed literature on primary cutaneous lymphomas involving the scalp, finding that scalp involvement in these cases often leads to non-scarring focal alopecia and may indicate more aggressive disease.

research Horizontal and vertical sections of scalp biopsy specimens from dermatomyositis patients with scalp involvement

16 citations , February 2018 in “Journal of The American Academy of Dermatology”

This study found that scalp involvement in dermatomyositis consistently shows a nonscarring pattern with chronic telogen effluvium, featuring telangiectasia and mucin deposition as universal histologic markers.

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Community Join

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...

39 upvotes 4 years ago

Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.

community Dutasteride + oral minoxidil: strong regrowth by Jan 2026, then mid-scalp density loss without current shedding

3 upvotes 5 months ago

The user experienced hair regrowth with dutasteride and oral minoxidil from October 2025 to January 2026, but mid-scalp density decreased afterward despite continued treatment. Ketoconazole improves scalp condition, but stopping it worsens hair appearance.

community My 5 months hair transplant update

in Progress Pictures 25 upvotes 5 months ago

A 39-year-old from Bangalore shared his successful hair transplant journey, which included 3537 scalp and 1521 beard grafts, boosting his confidence. He also started medication alongside the transplant.

community Need some advice on Hair Transplant

4 upvotes 2 weeks ago

The conversation is about planning a hair transplant in Turkey, with advice on choosing clinics and doctors, focusing on factors like doctor involvement, clinic reputation, and realistic graft limits per session. Users recommend not exceeding 4000 grafts per session to avoid donor area damage and suggest considering two separate procedures for better graft survival.

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