Erosive Pustular Dermatosis of the Scalp-Like Eruption Due to Gefitinib: Case Report and Review of Alopecia Associated with EGFR Inhibitors

    January 2012 in “ Dermatology ”
    Nagomi Toda, Noriki Fujimoto, Takeshi Kato … Toshihiro Tanaka
    Studysummary This case report describes how discontinuing the EGFR inhibitor gefitinib led to rapid improvement of erosive scalp pustules in a woman with non-small-cell lung cancer, despite previous antibiotic and steroid treatment failures.
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    Research cited in this study 10

    1. Scarring Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Erlotinib Journal of the American Academy of Dermatology · 2011
    2. A Case of Cicatricial Alopecia Associated with Erlotinib Annals of Dermatology · 2011
    3. Folliculitis Decalvans Associated with Erlotinib Clinical and Experimental Dermatology · 2010
    4. A Case Report of Inflammatory Nonscarring Alopecia Associated with the Epidermal Growth Factor Receptor Inhibitor Erlotinib Journal of Cutaneous Pathology · 2009
    5. Erlotinib-Associated Alopecia in a Lung Cancer Patient Journal of Thoracic Oncology · 2007
    6. Nonscarring Inflammatory Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Gefitinib Journal of the American Academy of Dermatology · 2006
    7. Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    8. Follicular and Epidermal Alterations in Patients Treated with ZD1839 (Iressa), an Inhibitor of the Epidermal Growth Factor Receptor British journal of dermatology/British journal of dermatology, Supplement · 2002
    9. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995
    10. Erosive Pustular Dermatosis of the Scalp British Journal of Dermatology · 1979

    Related research 2

    1. Bold to Do — Bald to Be? Outcomes Decades After Harvesting the Scalp in Burned Children Burns · 2018
    2. Incidental Syringomas of the Scalp in a Patient with Scarring Alopecia Case Reports in Dermatology · 2015