TLDR Erlotinib can cause hair loss and scalp issues, which improve after stopping the drug.
The article discussed a case of folliculitis decalvans, a rare form of scarring alopecia, associated with the use of erlotinib, a medication commonly used in cancer treatment. The patient developed pustules and hair loss on the scalp after starting erlotinib. The condition improved after discontinuing the drug and initiating treatment with antibiotics and topical steroids. This case highlighted the potential side effect of erlotinib on hair follicles, emphasizing the need for awareness among clinicians prescribing this medication.
25 citations
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January 2011 in “Annals of Dermatology” Erlotinib can cause hair loss as a side effect.
68 citations
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February 2015 in “Journal of the European Academy of Dermatology and Venereology” Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.
27 citations
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January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
July 2023 in “Dermatology practical & conceptual” Some lung cancer patients treated with EGFR inhibitors may develop a hair loss condition similar to folliculitis decalvans.
7 citations
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January 2023 in “Anti-Cancer Drugs” Early diagnosis and treatment of EGFR inhibitor-induced folliculitis decalvans can prevent permanent hair loss.