Folliculitis Decalvans Associated with Erlotinib

April 2010 in “ Clinical and Experimental Dermatology ”

Rick Hoekzema, Paul Drillenburg

folliculitis decalvans scarring alopecia erlotinib pustules hair loss antibiotics topical steroids hair follicles

TLDR Erlotinib can cause hair loss and scalp issues, which improve after stopping the drug.

The article discussed a case of folliculitis decalvans, a rare form of scarring alopecia, associated with the use of erlotinib, a medication commonly used in cancer treatment. The patient developed pustules and hair loss on the scalp after starting erlotinib. The condition improved after discontinuing the drug and initiating treatment with antibiotics and topical steroids. This case highlighted the potential side effect of erlotinib on hair follicles, emphasizing the need for awareness among clinicians prescribing this medication.

View this study on doi.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 57 results

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 36 upvotes 3 weeks ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 6 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Dutasteride Isn't Working? Get a Scalp Biopsy NOW

in Finasteride/Dutasteride 19 upvotes 2 weeks ago

Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.

community I tried salt water to stop the DHT itch

in Treatment 60 upvotes 2 years ago

Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

community Seb derm regrowth progress? I think? Or am I just seeing what I want to see?

in Is this regrowth? 48 upvotes 10 months ago

A person with hair loss due to seborrheic dermatitis saw improvement after treating the condition and using 5mg oral minoxidil, topical minoxidil, collagen, biotin, and vitamins. They are asking if the progress is real, and others have noted the oral minoxidil as a significant treatment.

Similar Research

5 / 1000+ results

research Folliculitis Decalvans: A Multicenter Review of 82 Patients

68 citations, February 2015 in “Journal of the European Academy of Dermatology and Venereology”

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

research Primary Scarring Alopecias

27 citations, January 2015 in “Current problems in dermatology”

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

research Folliculitis Decalvans-Like Alopecia During EGFR Inhibitors Treatment for Lung Cancer: A Case Series of 6 Patients

July 2023 in “Dermatology practical & conceptual”

Some lung cancer patients treated with EGFR inhibitors may develop a hair loss condition similar to folliculitis decalvans.

research Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

9 citations, August 2021 in “Journal of clinical medicine”

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

research Hair Changes Due to Drugs

July 2018 in “Elsevier eBooks”

Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.