Folliculitis Decalvans Associated with Erlotinib

    Rick Hoekzema, Paul Drillenburg
    TLDR Erlotinib can cause hair loss and scalp issues, which improve after stopping the drug.
    The article discussed a case of folliculitis decalvans, a rare form of scarring alopecia, associated with the use of erlotinib, a medication commonly used in cancer treatment. The patient developed pustules and hair loss on the scalp after starting erlotinib. The condition improved after discontinuing the drug and initiating treatment with antibiotics and topical steroids. This case highlighted the potential side effect of erlotinib on hair follicles, emphasizing the need for awareness among clinicians prescribing this medication.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 49 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 1 year ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

    Similar Research

    5 / 1000+ results
      Folliculitis Decalvans: A Multicenter Review of 82 Patients

      research Folliculitis Decalvans: A Multicenter Review of 82 Patients

      68 citations, February 2015 in “Journal of the European Academy of Dermatology and Venereology”
      Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.
      Primary Scarring Alopecias

      research Primary Scarring Alopecias

      27 citations, January 2015 in “Current problems in dermatology”
      The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
      Hair Changes Due to Drugs

      research Hair Changes Due to Drugs

      July 2018 in “Elsevier eBooks”
      Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.
      Diseases of Periocular Hair

      research Diseases of Periocular Hair

      7 citations, July 2011 in “Survey of Ophthalmology”
      The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.