Folliculitis Decalvans-Like Alopecia During EGFR Inhibitors Treatment for Lung Cancer: A Case Series of 6 Patients

    Michela Starace, Bianca Maria Piraccini, Miriam Anna Carpanese, Matilde Iorizzo, Zoe Apalla
    Image of study
    TLDR Some lung cancer patients treated with EGFR inhibitors may develop a hair loss condition similar to folliculitis decalvans.
    The document presents a case series involving 6 patients who developed a condition resembling folliculitis decalvans, a rare form of scarring alopecia, while undergoing treatment with epidermal growth factor receptor (EGFR) inhibitors for lung cancer. The study suggests a potential association between the use of EGFR inhibitors and the development of this alopecia-like condition. The findings indicate that patients receiving EGFR inhibitor therapy for lung cancer may be at risk of developing hair loss conditions that mimic folliculitis decalvans, highlighting the need for awareness among clinicians to manage this potential side effect. The study's conclusions are based on the observed cases, but the small sample size suggests that further research is needed to establish a definitive link and to understand the underlying mechanisms.
    Discuss this study in the Community →

    Research cited in this study

    2 / 2 results

    Related Community Posts Join

    6 / 52 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 3 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community I tried salt water to stop the DHT itch

      in Treatment  60 upvotes 2 years ago
      Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

    Similar Research

    5 / 1000+ results