Cancer-Related Alopecia Risk And Treatment

    Lily Kaufman, Lilia Valentic, Lucy Rose, Lucy Rose, Brittany Dulmage
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    TLDR Scalp cooling helps prevent hair loss during chemotherapy, and minoxidil aids regrowth.
    Cancer-related alopecia (CRA) significantly impacts patients' psychological well-being during cancer treatment. A personalized approach that includes prevention and regrowth strategies is essential. Scalp cooling is recommended as a first-line preventative measure for patients undergoing chemotherapy, particularly with taxane- or anthracycline-based regimens, due to its effectiveness in preserving hair. For those unable to use scalp cooling, early counseling and support are crucial. Topical minoxidil is the most evidence-based option for hair regrowth, while oral minoxidil requires caution due to limited safety data. Other treatments like spironolactone, tretinoin, prostaglandin analogs, and red light therapy may be considered in specific cases. A multidisciplinary, patient-centered approach is vital for optimizing CRA care.
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