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GlossaryTaxanes

chemotherapy drugs that disrupt cell division by stabilizing microtubules

Taxanes are a class of chemotherapy drugs that work by disrupting the normal function of microtubules, which are essential for cell division. By stabilizing these structures, taxanes prevent cancer cells from dividing and growing, making them effective in treating various types of cancer. However, they can also cause side effects like hair loss (alopecia) due to their impact on rapidly dividing cells in the body.

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research Cancer-Related Alopecia Risk And Treatment

July 2025 in “Current Treatment Options in Oncology”

Scalp cooling helps prevent hair loss during chemotherapy, and minoxidil aids regrowth.

research Low-Intensity Ultrasound Protects Human Scalp Hair Follicles From Taxane-Induced Toxicity

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Low-intensity ultrasound may protect hair follicles from damage caused by a common chemotherapy drug.

Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients

research Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients

31 citations , March 2017 in “Journal of The American Academy of Dermatology”

Some breast cancer patients developed permanent hair loss after chemotherapy and hormonal therapy, showing patterns similar to common baldness and alopecia areata.

research Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-Induced Cytotoxicity

11 citations , January 2022 in “Journal of Cancer”

Low intensity ultrasound may reduce side effects of chemotherapy drugs like paclitaxel.

research Permanent Alopecia Post-Chemotherapy with Favorable Response to Topical Minoxidil

December 2017 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia”

Topical minoxidil may help regrow hair after permanent hair loss from chemotherapy.

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