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    Glossary Taxanes

    chemotherapy drugs that disrupt cell division by stabilizing microtubules

    Taxanes are a class of chemotherapy drugs that work by disrupting the normal function of microtubules, which are essential for cell division. By stabilizing these structures, taxanes prevent cancer cells from dividing and growing, making them effective in treating various types of cancer. However, they can also cause side effects like hair loss (alopecia) due to their impact on rapidly dividing cells in the body.

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    Research 10 of 415

    1. Dermatological adverse events with taxane chemotherapy European Journal of Dermatology · 2016 · 141 citations
    2. CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia EMBO Molecular Medicine · 2019 · 58 citations
    3. Permanent alopecia in patients with breast cancer after taxane chemotherapy and adjuvant hormonal therapy: Clinicopathologic findings in a cohort of 10 patients Journal of The American Academy of Dermatology · 2017 · 31 citations
    4. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Nutrients · 2018 · 19 citations
    5. Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-induced Cytotoxicity Journal of Cancer · 2022 · 11 citations
    6. Madarosis: a qualitative study to assess perceptions and experience of Australian patients with early breast cancer treated with taxane-based chemotherapy Supportive care in cancer · 2017 · 11 citations
    7. Low-Intensity Ultrasound as a Potential Intervention Strategy to Protect Human Scalp Hair Follicles from Taxane-Induced Toxicity Journal of Investigative Dermatology · 2023 · 7 citations
    8. Taxane-induced alopecia: A historical review of patients with ovarian or breast cancer treated with with paclitaxel, docetaxel or paclitaxel poliglumex Journal of Clinical Oncology · 2005 · 5 citations
    9. Persistent Alopecia in a Breast Cancer Patient Following Taxane Chemotherapy and Adjuvant Endocrine Therapy: Case Report and Review of Post-treatment Hair Loss in Oncology Patients with Breast Cancer Cureus · 2018 · 3 citations
    10. Permanent Alopecia in Breast Cancer Patients: Role of Taxanes and Endocrine Therapies Cutis · 2021 · 2 citations
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