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    Glossary Taxanes

    chemotherapy drugs that disrupt cell division by stabilizing microtubules

    Taxanes are a class of chemotherapy drugs that work by disrupting the normal function of microtubules, which are essential for cell division. By stabilizing these structures, taxanes prevent cancer cells from dividing and growing, making them effective in treating various types of cancer. However, they can also cause side effects like hair loss (alopecia) due to their impact on rapidly dividing cells in the body.

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    Research 10 of 279

    1. Dermatological adverse events with taxane chemotherapy European Journal of Dermatology · 2016 · 141 citations
    2. CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia EMBO Molecular Medicine · 2019 · 58 citations
    3. Permanent alopecia in patients with breast cancer after taxane chemotherapy and adjuvant hormonal therapy: Clinicopathologic findings in a cohort of 10 patients Journal of The American Academy of Dermatology · 2017 · 31 citations
    4. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Nutrients · 2018 · 19 citations
    5. Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-induced Cytotoxicity Journal of Cancer · 2022 · 11 citations
    6. Low-Intensity Ultrasound as a Potential Intervention Strategy to Protect Human Scalp Hair Follicles from Taxane-Induced Toxicity Journal of Investigative Dermatology · 2023 · 7 citations
    7. Taxane-induced alopecia: A historical review of patients with ovarian or breast cancer treated with with paclitaxel, docetaxel or paclitaxel poliglumex Journal of Clinical Oncology · 2005 · 5 citations
    8. Permanent Alopecia in Breast Cancer Patients: Role of Taxanes and Endocrine Therapies Cutis · 2021 · 2 citations
    9. Mechanism-Based Strategies for Prevention of Taxane-Induced Hair Follicle Damage in Cancer Chemotherapy Cancers · 2026
    10. 506 Taxane chemotherapy promotes aging of human hair follicles and their stem cells Journal of Investigative Dermatology · 2024
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