Alopecia in Patients Treated with Molecularly Targeted Anticancer Therapies

    September 2015 in “ Annals of Oncology ”
    Viswanath Reddy Belum, Kathleen Marulanda, Courtney J. Ensslin … Mario E. Lacouture
    Studysummary This study reported that targeted anticancer therapies are associated with an increased risk of alopecia compared to placebo, although the risk was lower compared to chemotherapy.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 12

    1. A Hospital-Based Study to Determine Causes of Diffuse Hair Loss in Women Journal of Clinical and Diagnostic Research · 2015
    2. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    3. Androgenetic Alopecia in Policemen: Higher Prevalence and Different Risk Factors Relative to the General Population (KCIS No. 23) Archives of Dermatological Research · 2011
    4. Scarring Alopecia Associated With the Epidermal Growth Factor Receptor Inhibitor Erlotinib Journal of the American Academy of Dermatology · 2011
    5. Cetuximab-Associated Elongation of the Eyelashes American Journal of Clinical Dermatology · 2010
    6. Folliculitis Decalvans Associated with Erlotinib Clinical and Experimental Dermatology · 2010
    7. Chemotherapy-Induced Alopecia: Emotional Distress and Mitigation Strategies Seminars in Cutaneous Medicine and Surgery · 2009
    8. PDGF Isoforms Induce and Maintain Anagen Phase of Murine Hair Follicles Journal of Dermatological Science · 2006
    9. Conditional Disruption of Hedgehog Signaling Pathway Defines Its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000
    10. Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development PubMed · 1997
    11. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    12. Comparison of Epidermal Growth Factor Binding and Receptor Distribution in Normal Human Epidermis and Epidermal Appendages Journal of Investigative Dermatology · 1984