Dermatologic Adverse Events in Pediatric Patients Receiving Targeted Anticancer Therapies: A Pooled Analysis

    February 2015 in “ Pediatric blood & cancer
    Viswanath Reddy Belum, Courtney Washington, Christine A. Pratilas … Mario E. Lacouture
    Studysummary This study analyzed 19 clinical trials and found that dermatologic adverse events, such as rash, xerosis, and mucositis, frequently occur in pediatric patients receiving targeted anticancer therapies.
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    Research cited in this study 4

    1. Advances in the Management of Cutaneous Toxicities of Targeted Therapies Seminars in Oncology · 2012
    2. Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors Supportive Care in Cancer · 2012
    3. Genetically Null Mice Reveal a Central Role for Epidermal Growth Factor Receptor in the Differentiation of the Hair Follicle and Normal Hair Development PubMed · 1997
    4. Immunolocalization of Epidermal Growth Factor Receptors in Normal Developing Human Skin Journal of Investigative Dermatology · 1990