Weight Gain and Hair Loss During Anti-TNF Therapy

The study investigated weight gain and hair loss as adverse effects of anti-TNF therapy in 150 patients with rheumatic diseases. Weight gain was observed in 20 patients (13.3%) with an average gain of 5.5 kg, leading to discontinuation of therapy in five cases. Hair loss was reported in five females (3.3%), and all discontinued the therapy. The findings suggested that weight gain and hair loss were associated with anti-TNF therapy and could be reasons for stopping the treatment.