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    GlossaryDrug-Induced Lupus Erythematosus

    condition where certain medications trigger lupus-like symptoms

    Drug-Induced Lupus Erythematosus (DILE) is a condition where certain medications trigger symptoms similar to those of systemic lupus erythematosus (SLE), such as joint pain, muscle pain, and fatigue. Unlike SLE, DILE typically resolves once the offending drug is discontinued. Common drugs associated with DILE include hydralazine, procainamide, and isoniazid.

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      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Dutasteride

      Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Minoxidil Finasteride heart problems

      in Update  97 upvotes 6 months ago
      A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.