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    Glossary Drug Reaction with Eosinophilia and Systemic Symptoms

    severe allergic reaction to medication causing rash and organ damage

    Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a severe, potentially life-threatening hypersensitivity reaction to certain medications. It is characterized by a widespread skin rash, fever, swollen lymph nodes, and involvement of internal organs such as the liver, kidneys, and lungs. Eosinophilia, an elevated level of a type of white blood cell called eosinophils, is a hallmark of this condition. Early recognition and discontinuation of the offending drug are crucial for managing DRESS.

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    1. Drug reaction with eosinophilia and systemic symptoms and severe involvement of digestive tract: description of two cases British Journal of Dermatology · 2011 · 19 citations
    2. HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms Elsevier eBooks · 2014 · 2 citations
    3. Baricitinib for Alopecia Universalis Following Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms Eurasian Journal of Medicine · 2026
    4. 392 Hair loss after drug reaction with eosinophilia and systemic symptoms: A multicentric retrospective study Journal of Investigative Dermatology · 2023
    5. Long-term sequelae of drug reaction with eosinophilia and systemic symptoms: A retrospective cohort study from Taiwan Journal of the American Academy of Dermatology · 2012 · 157 citations
    6. Hair loss after drug reaction with eosinophilia and systemic symptoms (DRESS): A multicentric retrospective case series Journal of Dermatology · 2023 · 2 citations
    7. Viral reactivation in hospitalized patients with drug reaction with eosinophilia and systemic symptoms: A retrospective study from a tertiary medical center in the United States Journal of the American Academy of Dermatology · 2020 · 14 citations
    8. Relapsing Course of Sulfasalazine-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Complicated by Alopecia Universalis and Vitiligo Annals of the Academy of Medicine Singapore · 2018 · 18 citations
    9. Six-year Retrospective Review of Drug Reaction with Eosinophilia and Systemic Symptoms Acta dermato-venereologica · 2012 · 39 citations
    10. Aggressive treatment in paediatric or young patients with drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is associated with future development of type III polyglandular autoimmune syndrome BMJ Case Reports · 2018 · 33 citations
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