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    Glossary Acute Generalized Exanthematous Pustulosis

    rare skin reaction with rapid onset of small, sterile pustules

    Acute Generalized Exanthematous Pustulosis (AGEP) is a rare skin reaction characterized by the rapid onset of numerous small, sterile pustules on a background of red, inflamed skin. It is often triggered by medications, such as antibiotics, and typically resolves within a few weeks after discontinuing the offending drug.

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    1. Acute generalized exanthematous pustulosis induced by hydroxychloroquine prescribed for COVID-19 The Journal of Allergy and Clinical Immunology In Practice · 2020 · 26 citations
    2. Flagellate Shiitake Mushroom Reaction With Histologic Features of Acute Generalized Exanthematous Pustulosis Cutis · 2021 · 2 citations
    3. 567 Acute generalized exanthematous pustulosis (AGEP) induced by plaquenil Journal of Investigative Dermatology · 2024 · 1 citations
    4. Confirmation of Metformin-Induced Acute Generalized Exanthematous Pustulosis Through a Positive Dechallenge-Rechallenge Test: A Case Report and Review of Cutaneous Manifestations Associated With Metformin Cureus · 2025
    5. COVID-19 infection leading to acute pustular dermatoses Archives of Dermatological Research · 2022 · 12 citations
    6. Acute Localised Exanthematous Pustulosis Indian Journal of Dermatology · 2022 · 3 citations
    7. Severe cutaneous adverse reactions to drugs The Lancet · 2017 · 273 citations
    8. Pustular allergic contact dermatitis caused by fragrances Contact dermatitis · 2015 · 19 citations
    9. Semaglutide-Induced Atypical Pustular Drug Eruption: A Case Report Cureus · 2026
    10. Etoricoxib Reactions Weekly · 2012
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