The Hair Loss Encyclopedia

T Cell–Mediated Acute Localized Exanthematous Pustulosis Caused by Finasteride

February 2012 in “ The Journal of Allergy and Clinical Immunology ”

Sandra Tresch, Antonio Cozzio, Jivko Kamarashev, Thomas Harr, Peter Schmid-Grendelmeier, Lars E. French, Laurence Feldmeyer

finasteride acute localized exanthematous pustulosis ALEP drug hypersensitivity reactions lymphocyte transformation test acute generalized exanthematous pustulosis AGEP Propecia

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TLDR Finasteride caused a rare skin rash in a man, which improved after stopping the medication.

A 21-year-old man developed a pruritic rash on his upper trunk and neck after taking finasteride for hair loss. A lesional biopsy showed acute localized exanthematous pustulosis (ALEP), a rare skin condition primarily caused by drug reactions. The rash resolved after discontinuing the medication, and a lymphocyte transformation test confirmed the reaction to finasteride. The article discusses the differential diagnosis of ALEP and the pathophysiology of drug hypersensitivity reactions. The authors suggest that ALEP may be an independent entity from acute generalized exanthematous pustulosis (AGEP), but more research is needed.

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Research cited in this study

5 / 5 results

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4 citations, February 1996 in “Postgraduate Medical Journal”

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Related Community Posts Join

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community My story: Trying to halt diffuse hair loss for past couple of years but got acute hair fall after quitting minoxidil and finasteride on my dermatologist recommendation

in Chat 9 upvotes 2 days ago

A 22-year-old man experienced significant hair loss after stopping minoxidil and finasteride, causing emotional distress. He resumed these treatments and is considering dutasteride and microneedling to manage his hair loss.

community Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?

in Finasteride 6 upvotes 6 years ago

The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.

community Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early

in Finasteride/Dutasteride 247 upvotes 1 year ago

The conversation discusses the effectiveness of finasteride and dutasteride in treating hair loss, emphasizing that significant results often take 12-18 months or more. Dutasteride is generally considered superior, with similar or fewer side effects than finasteride, but patience is required for noticeable improvement.

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Erythema Annulare Centrifugum Secondary to Treatment with Finasteride

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7 citations, April 2007 in “PubMed”

Finasteride, a hair loss drug, caused a skin rash that went away when the drug was stopped and returned when used again.