Search
for

    Glossary Phase II metabolism

    body adds molecules to drugs/toxins for easier excretion

    Phase II metabolism, also known as conjugation reactions, is a process where the body adds a molecule to a drug or toxin to make it more water-soluble and easier to excrete. This phase typically follows Phase I metabolism, which involves the modification of the substance. By making these compounds more water-soluble, the body can more efficiently eliminate them through urine or bile, reducing their potential toxicity.

    Related Terms

    Research 10 of 1000+

    1. The effect of St. John’s wort treatment on finasteride pharmacokinetics and identification of new phase I and phase II metabolites in humans 2008
    2. Chapter 14 Principles of drug metabolism Principles of Medical Biology · 1997 · 2 citations
    3. High-resolution mass spectrometric investigation of the phase I and II metabolites of finasteride in pig plasma, urine and bile Xenobiotica · 2013 · 2 citations
    4. Identification of Metabolites for the Novel 5α‐Reductase Inhibitor Epristeride In Vitro and Its Potential Impact on Doping Testing Drug Testing and Analysis · 2025
    5. The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity. PubMed · 2019 · 4 citations
    6. 138 Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles 2017
    7. Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures bioRxiv (Cold Spring Harbor Laboratory) · 2018
    8. Analysis of metabolic characteristics of epristeride in zebrafish based on LC-Q-TOF MS and its potential applications in doping control RSC Advances · 2026
    9. Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry Drug Metabolism and Disposition · 2009 · 18 citations
    10. Comparison of Activities Dependent on Glutathione S-Transferase and Cytochrome P-450 IA1 in Cultured Keratinocytes and Reconstructed Epidermal Models Skin Pharmacology and Physiology · 2002 · 42 citations
    All research results →

    Learn 1 of 27

    1. RU58841 Experimental topical anti-androgen sold as a research chemical
    All learn results →

    Community 10 of 420

    1. Phase II topical dut study - outperforms oral fin with a minor DHT reduction Reddit · 10 Feb 2026
    2. GT20029 phase II results release date? Reddit · 9 Jan 2024
    3. About Pyrilutamide Phase II US Trial Reddit · 13 Sept 2023
    4. KX-826 1% Phase II Results from China Just Dropped Reddit · 31 Jul 2025
    5. KX-826 Phase II Results Just Dropped (Male AGA) – Key Takeaways Reddit · 28 Jul 2025
    6. GT20029 - Promising phase II results Reddit · 28 Apr 2024
    7. GT20029 China Phase II Trial For AGA Reached Primary Endpoint Reddit · 21 Apr 2024
    8. Where are GT20029 phase II results? Reddit · 7 Dec 2023
    9. Kintor Pharma Announces Completion of Patient Enrollment in Phase II Clinical Trial of GT20029 for Treatment of Androgenetic Alopecia in China Reddit · 22 Aug 2023
    10. So why did the first pyrilutamide phase III fail? Reddit · 7 Aug 2026
    All community results →