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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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chemical from L'Oreal that encourages hair to enter growth phase
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nucleoside used for hair regrowth stimulant properties
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Microscopic delivery system that sends growth-promoting signals to hair follicles
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research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
research Finasteride Delays Atherosclerosis Progression in Mice and Is Associated With a Reduction in Plasma Cholesterol in Men
Finasteride may lower cholesterol and slow heart disease progression.
research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Extracellular vesicles could help tailor drug treatments, but more research is needed.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
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community The story of RU58841/ PSK3841
by
Typical-Promise-3001
in Research
622 upvotes
1 year ago RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
community Update on my progress after 5 month of taking fin/min
The user has been taking 1 mg of finasteride and 6 drops of minoxidil orally per day for five months, experiencing increased hair shedding but also noticing denser and fuller hair according to friends. Despite the shedding, the user is happy with the progress and has not experienced significant side effects, though they caution against the risks of taking minoxidil orally.
community Long time users of Dut/Fin, what would you do differently if you had to start all over?
People shared experiences with hair loss treatments like Minoxidil, Finasteride, and Dutasteride. Opinions varied on effectiveness and side effects, with advice to start early and adjust dosages based on individual reactions.
community Anyone here have a lot of knowledge on hair follicle stem cells and progenitor cells for PP405?
Hair follicle stem cells remain in bald individuals, but progenitor cells do not, raising questions about hair regrowth claims by Pelage. PP405 is discussed as a potential treatment, with skepticism about its effectiveness compared to existing treatments like Minoxidil and Finasteride.
community The Cure isn't 5 years away; it's already here.
PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.