Search

for
Search:

Glossary Biotransformation

process of chemically altering substances in the body

Biotransformation is the process by which the body chemically alters substances, such as drugs or toxins, to make them easier to eliminate. This typically occurs in the liver and involves enzymatic reactions that convert these substances into more water-soluble compounds, facilitating their excretion through urine or bile.

Related Terms

Research

5 / 254 results

research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs

36 citations , June 2019 in “eLife”

This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.

research Metabolism of Minoxidil, a New Hypotensive Agent 11: Biotransformation following Oral Administration to Rats, Dogs, and Monkeys

31 citations , August 1975 in “Journal of Pharmaceutical Sciences”

This study found that different species metabolized minoxidil into various products, with monkeys and humans showing similar profiles primarily excreting a glucuronide conjugate, while rats and dogs showed distinct differences.

research Biotransformation of Finasteride by Ocimum sanctum L., and tyrosinase inhibitory activity of transformed metabolites: Experimental and computational insights

3 citations , August 2014 in “Steroids”

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

research Biotransformation of tirilazad in human: 4. effect of finasteride on tirilazad clearance and reduced metabolite formation.

3 citations , November 1998 in “PubMed”

This study found that finasteride significantly inhibits the metabolism of tirilazad to its active metabolites without greatly affecting tirilazad's overall clearance.

research Bio-Catalytic Action of Pseudomonas DL17 on Environmental Contaminant Sunset Yellow FCF

2 citations , July 2020 in “International Journal for Research in Applied Science and Engineering Technology”

This study found that Pseudomonas DL7 completely degraded 600 mg/L of Sunset Yellow FCF in 48 hours at pH 9, indicating potential for biomineralization of this dye.

View more "biotransformation" in research →

Learn

— no results

Try a deeper search in learn →

Community Join

— no results

Try a deeper search in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →