Metabolism of Minoxidil, a New Hypotensive Agent: Biotransformation Following Oral Administration to Rats, Dogs, and Monkeys

    Richard F. Thomas, Harry Harpootlian
    Studysummary This study found that different species metabolized minoxidil into various products, with monkeys and humans showing similar profiles primarily excreting a glucuronide conjugate, while rats and dogs showed distinct differences.
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    Research cited in this study 1

    1. Pharmacokinetic Studies of Minoxidil Clinical Pharmacology & Therapeutics · 1972