Chapter 14: Principles of Drug Metabolism
January 1997
in “
Principles of Medical Biology
”
drug metabolism mixed-function oxidase enzyme system cytochrome P450 enzymes Phase I metabolic processes Phase II metabolic processes enzyme-catalyzed reactions genetic polymorphism N-acetyltransferase monoamine oxidase MAO inhibitors mixed-function oxidase CYP450 enzymes Phase I metabolism Phase II metabolism enzyme reactions genetic variation NAT MAO MAOIs
Studysummary This article reviews the role of enzymatic processes in drug and toxin metabolism, emphasizing their impact on solubility and elimination, without presenting new clinical findings.
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