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GlossaryCytochrome P450 (P450 enzymes)

enzymes metabolize drugs and toxins in the liver

Cytochrome P450 (CYP) refers to a large family of enzymes that play a crucial role in the metabolism of various substances within the body, including drugs, toxins, and hormones. These enzymes are primarily found in the liver and are essential for the detoxification process, as well as the synthesis of cholesterol, steroids, and other lipids.

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research Chapter 14: Principles of Drug Metabolism

2 citations , January 1997 in “Principles of Medical Biology”

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

research Protective Role of Melatonin and Its Metabolites in Skin Aging

32 citations , January 2022 in “International Journal of Molecular Sciences”

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases

51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Systemic Antifungals: Overview, Applications, and Costs

January 2018 in “Springer eBooks”

Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.

research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality

7 citations , August 2023 in “Life”

Extracellular vesicles could help tailor drug treatments, but more research is needed.

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community Methods Of Staying Safe On Ru58841 - My 2 Cents

in Research/Science 21 upvotes 1 year ago

RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

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in Research/Science 109 upvotes 2 years ago

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