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Glossary Telogen Follicles

hair follicles in the resting phase of the growth cycle

Telogen follicles, also known as resting hair follicles, are hair follicles in the final phase of the hair growth cycle, called the telogen phase. During this phase, hair growth stops, and the hair is eventually shed to make way for new growth. This phase typically lasts around 2-3 months, and it is normal for about 10-15% of hair follicles to be in the telogen phase at any given time.

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Research

5 / 1000+ results

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations , August 2020 in “Genes”

This study mapped gene expression in different skin structures of dogs, finding similarities to humans that support using dogs as models for human skin diseases.

research Compound Follicles in Folliculitis Decalvans Do Not Contain Vellus and Retained Telogen Follicles—A Pilot Histopathologic Series on Polytrichia

October 2024 in “Journal of Cutaneous Pathology”

In this study of folliculitis decalvans, researchers found that compound follicular structures in scalp biopsies are primarily composed of terminal anagen follicles, surrounded by fibrosis and inflammatory cell infiltrate, which could enhance understanding of this condition.

research The Proportion of Catagen and Telogen Hair Follicles in Occipital Scalp of Male Androgenetic Alopecia Patients: Challenging the Established Dogma

October 2024 in “Experimental Dermatology”

This study examined hair follicles from 14 Caucasian males and found that catagen-phase follicles were more prevalent (7.5%) than previously reported, challenging the established view that telogen-phase follicles are more common.

research The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles

35 citations , February 2019 in “Cell Communication and Signaling”

This study found that BMP6 and Wnt10b competitively regulate the transition between hair follicle growth phases, offering new insights into hair follicle cycling and potential hair loss treatments.

research Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo

25 citations , June 2004 in “Journal of Investigative Dermatology”

This study found that macrophage-stimulating protein (MSP) enhanced hair growth in both human hair follicles cultured in vitro and in mice through the promotion of anagen phase induction.

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Community Join

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community Tretinoin for some men(not all) can cause non-telogen effluvium hair loss

in Research/Science 5 upvotes 1 year ago

Tretinoin can cause non-telogen hair loss in some men by inducing catagen-like changes in hair follicles and through retinoid toxicity, especially when used with minoxidil. Some users report hair loss even when using retinoids on the face, while others experience benefits when combined with treatments like finasteride and minoxidil.

community Another mechanism to hair loss that isn’t talked about. Heavy metals and follicle waste.

16 upvotes 3 months ago

Hair follicles can store waste, potentially leading to hair loss, and treatments like DHT blockers and Minoxidil are suggested. Scalp inflammation and sensitivity to DHT also contribute to hair loss, and addressing these factors with a clinician is recommended.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

7 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Is 2years+ telogen effluvium possible?

in Finasteride/Dutasteride 2 upvotes 2 years ago

The user has been losing hair for over two years despite taking dutasteride and RU58841, even increasing dutasteride to 2.5mg. They are questioning if their hair loss could be due to telogen effluvium instead.

community Can pp405 revive dead follicles for long time bald people? Are those even dead? After 10+ years bald

47 upvotes 1 year ago

PP405 may revive dormant hair follicles but is unlikely to help with long-term baldness where follicles are replaced by scar tissue. It is seen as a potential adjunct to treatments like minoxidil and finasteride, but its effectiveness on deeply fibrotic or scarred areas is doubtful.

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