Alopecia Areata Following Adalimumab

    Carly Kirshen, Nordau Kanigsberg
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    TLDR A woman developed hair loss after starting a treatment with adalimumab, suggesting this medication might cause hair loss.
    The document described a case where a 52-year-old woman with psoriatic arthritis developed alopecia areata after beginning treatment with adalimumab, a TNF-α inhibitor. This was the first reported instance of alopecia areata onset following adalimumab treatment. The case contributed to the unexpected link between TNF-α inhibitors and alopecia areata, challenging the previously held belief that TNF-α plays a role in the disease's pathogenesis. It suggested that blocking TNF-α might disrupt immune balance, causing inflammation and hair loss. The paper emphasized the need for clinicians to consider the possibility of TNF-α blockers inducing alopecia areata in patients.
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