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Glossary Ulcerative Colitis

chronic inflammatory bowel disease affecting the colon and rectum

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease (IBD) that primarily affects the colon and rectum, causing inflammation and ulcers in the lining of the large intestine. Symptoms often include abdominal pain, diarrhea mixed with blood, and an urgent need to defecate. The exact cause is unknown, but it is believed to involve an abnormal immune response, genetic factors, and environmental triggers.

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Research

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research Ulcerative colitis and total alopecia in a mother and her son

23 citations , April 1993 in “Gastroenterology”

This study reported a case where cyclosporine treatment in a child led to remission of ulcerative colitis and regrowth of scalp and body hair, suggesting a possible connection between the disorders.

research Incidental benefits after fecal microbiota transplant for ulcerative colitis

15 citations , April 2020 in “Intestinal Research”

This study observed that fecal microbiota transplantation for ulcerative colitis may also offer incidental benefits such as weight loss, improved hair loss, and relief from axial arthritis and allergic rhinitis.

research Alopecia Universalis Associated with Ulcerative Colitis and The Role of Azathioprine

8 citations , January 2018 in “Middle East Journal of Digestive Diseases”

This case report describes a middle-aged man with alopecia universalis and ulcerative colitis, where hair regrowth occurred following treatment with azathioprine and mesalamine.

research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats

3 citations , January 2021 in “Oxidative Medicine and Cellular Longevity”

In this study, Nrf-2-expressing hair follicle mesenchymal stem cells showed the most significant therapeutic effect in a rat model of ulcerative colitis, suggesting a new potential treatment for the disease.

research Two cases in which tofacitinib effectively treated both ulcerative colitis and alopecia areata

2 citations , June 2020 in “Clinical Journal of Gastroenterology”

This case report describes two patients with ulcerative colitis and alopecia areata who did not respond to various treatments but achieved remission and improved hair growth after starting tofacitinib.

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Learn

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learn Tofacitinib

What is tofacitinib, and why is it discussed in relation to autoimmune-related hair loss such as alopecia areata? Tofacitinib is a prescription JAK inhibitor approved for rheumatoid arthritis, psoriatic arthritis and ulcerative colitis — not for alopecia areata. It is discussed for hair loss because a 2014 case report and a 2016 open-label trial reported regrowth in severe alopecia areata, but that use is off-label, the regrowth relapsed after stopping, and the drug carries an FDA boxed warning.

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Community Join

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community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 1 year ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community Does anyone think their hair loss is thyroid related?

10 upvotes 1 year ago

Hair loss may be linked to thyroid issues, with some individuals noticing changes in hair texture when taking substances affecting the thyroid. Treatments mentioned include a topical mix of finasteride, minoxidil, and tretinoin, along with microneedling.

community I just made 60x of 5mg minoxidil sugar cubes

1339 upvotes 1 year ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community What else is good. Besides the big 3.

in Chat 35 upvotes 1 year ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

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