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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community Xeljanz medication for alopecia universalis?

       4 upvotes 2 months ago
      A person with alopecia universalis is considering using Xeljanz but is advised that Olumiant is more effective for their condition. They are under a dermatologist's care and should expect gradual progress, as follicles dormant for 20 years are challenging to reactivate.

      community Alopecia Areata Question

       2 upvotes 5 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

    Research

    5 / 155 results
      Tofacitinib for the Treatment of Alopecia Areata and Variants in Adolescents

      research Tofacitinib for the treatment of alopecia areata and variants in adolescents

      139 citations , November 2016 in “Journal of the American Academy of Dermatology”
      In this retrospective review, tofacitinib treatment was associated with clinically significant hair regrowth in most adolescent patients with alopecia areata, though limitations suggest further studies are needed to confirm these findings.

      research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

      88 citations , August 2019 in “Frontiers in immunology”
      This review discusses the role of tyrosine kinase signaling pathways in autoimmune and inflammatory skin diseases and reports no new clinical results, highlighting ongoing research into small-molecule tyrosine kinase inhibitors as potential treatments.