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    GlossaryArachidonic Acid

    polyunsaturated omega-6 fatty acid involved in inflammation and signaling

    Arachidonic Acid (AA) is a polyunsaturated omega-6 fatty acid that is a key component of cell membranes. It plays a crucial role in the body's inflammatory response and is a precursor to various signaling molecules called eicosanoids, which include prostaglandins, thromboxanes, and leukotrienes. These molecules are involved in processes such as inflammation, immunity, and the regulation of blood pressure.

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      community Painkillers May Block Minoxidil

      in Research/Science  16 upvotes 1 week ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Why is there no feedback on pge2/setipiprant?

      in Question  6 upvotes 8 years ago
      The conversation questions the lack of feedback on the effectiveness of PGE2 and setipiprant for hair loss, despite their availability. The user is puzzled by the absence of reviews or results, whether positive or negative.