This study describes a computational method using side-effect data from social media to identify new drug indications, suggesting it could be effective for drug repositioning.
April 2002 in “Annals of Internal Medicine” This study reported that patients experiencing hypertriglyceridemia during isotretinoin therapy for acne are at higher risk for developing hyperlipidemia and metabolic syndrome.
May 2024 in “Indian Journal of Pharmacology” In this case report, an 11-year-old girl with alopecia totalis initially treated with minoxidil experienced hypertrichosis, which reversed upon stopping the medication; hair regrowth on the scalp was achieved with tofacitinib after minoxidil discontinuation.
November 2022 in “International Journal of Trichology” This case study reports a 25-year-old male developing an extensive psoriasiform eruption within a week after starting finasteride 1 mg for androgenetic alopecia.
This study developed a computational method using side-effect data from social media to identify potential new drug indications, showing that it successfully recovered known and trial indications.