A Clinical Study of Mucocutaneous Manifestations of HIV

September 2014 in “ Journal of evolution of medical and dental sciences ”

S B Murugesh, Nandini A.S, K Ravindra, N Ramya

oral candidiasis HSV dermatophytosis xerosis hyperpigmentation seborrheic dermatitis diffuse alopecia trichomegaly melanonychia oral thrush herpes simplex virus fungal infection dry skin skin darkening seborrhea hair loss long eyelashes black nails

Studysummary In this study, 92% of HIV-infected patients had mucocutaneous manifestations, with oral candidiasis being the most common condition observed. Our plain-language summary of this paper — not a Tressless recommendation.

The study, conducted over a period from September 2004 to June 2006, included 150 HIV seropositive patients, of whom 92% exhibited mucocutaneous manifestations at the time of examination. The age range of the majority of patients was 25-49 years, with a slightly higher number of males than females. Oral candidiasis was the most prevalent condition, affecting 33.33% of the patients, followed by various other infections such as HSV and dermatophytosis. Non-infectious conditions like generalized xerosis, hyperpigmentation, and seborrheic dermatitis were also common. Notably, 18% of patients experienced diffuse alopecia, and other hair and nail changes were observed, including trichomegaly and melanonychia. The study did not include CD4 count correlations due to lack of facilities and emphasized the importance of dermatological care in HIV patients for early management and improved quality of life.

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Research cited in this study

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research Clinical and Histopathologic Features of Hair Loss in Patients with HIV-1 Infection

46 citations , January 1996 in “Journal of The American Academy of Dermatology”

This study identified the presence of apoptotic or necrotic keratinocytes and hair shaft dystrophy as potential markers of hair loss in patients with HIV-1 infection.