Mucocutaneous Manifestations in HIV-Infected Patients and Their Relationship to CD4 Lymphocyte Counts

    August 2020 in “ Scientifica ”
    Mina Mirnezami, Nader Zarinfar, Masoomeh Sofian, Bahareh Botlani Yadegar, Hamzeh Rahimi
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    Studysummary This study found that a high percentage of HIV-positive patients experienced mucocutaneous lesions, with conditions like oral candidiasis and furuncle being significantly associated with lower CD4 cell counts. Our plain-language summary of this paper — not a Tressless recommendation.
    In the cross-sectional study involving 84 HIV-positive patients, researchers discovered that 95.2% exhibited at least one mucocutaneous lesion, with the most frequent being xerosis, seborrheic dermatitis, herpes simplex, and oral candidiasis. The presence of oral candidiasis and furuncles was significantly linked to lower CD4 cell counts. The findings indicated that certain skin conditions, especially oral candidiasis and furuncles, could act as indicators of immune status in HIV-infected individuals, highlighting the need for routine skin examinations in their medical care.
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