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    Glossary Interleukin-1 alpha

    promotes inflammation and influences hair follicle biology

    Interleukin-1 alpha (IL-1α) is a type of protein known as a cytokine, which plays a crucial role in the body's immune response by promoting inflammation. It is involved in various cellular activities, including cell proliferation, differentiation, and apoptosis. In the context of hair and alopecia, IL-1α can influence hair follicle biology and has been implicated in inflammatory conditions that may lead to hair loss.

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    1. Minoxidil downregulates Interleukin-1 alpha gene expression in HaCaT cells International Journal of Trichology · 2018 · 16 citations
    2. Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice Inflammation and Regeneration · 2023 · 7 citations
    3. IL-1 alpha inhibits human hair follicle growth and hair fiber production in whole-organ cultures. PubMed · 1993 · 30 citations
    4. Distribution of human B-defensin 2, TNF-alpha, IL-1 alpha, IL-6 and IL-8 in psoriatic skin Papers on Anthropology · 2012 · 1 citations
    5. Serum levels of interleukin-1 (IL-1α, IL-1β) in patients with alopecia areata Nasza Dermatologia Online · 2012 · 1 citations
    6. Myrtus communis Leaf Extract Modulates IL-1α and VEGF Gene Expressions in HaCaT Cells: Probable Implications for Its Beneficial Effects in Hair Loss and Wound Healing Dove Medical Press (Taylor and Francis Group) · 2026
    7. Myrtus communis Leaf Extract Modulates IL-1α and VEGF Gene Expressions in HaCaT Cells: Probable Implications for Its Beneficial Effects in Hair Loss and Wound Healing SHILAP Revista de lepidopterología · 2026
    8. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    9. Detection of Serum Levels of Interleukins-17, 21, 6 and Tumor Necrosis Factor-α in Patients with Patchy Alopecia Areata and Their Association with Disease Severity Diseases · 2025
    10. Investigation of the Gene Expression Levels of 5 α-reductase, VEGF and IL-1α in HaCaT Cells after the Application of a Botanical Extract Journal of Dermatology and Venereology · 2014 · 1 citations
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    1. NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress Reddit · 9 Jun 2024

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