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Glossary Inflammatory Genes

segments of DNA that regulate the body's inflammatory response

Inflammatory genes are segments of DNA that encode proteins involved in the body's inflammatory response, which is the immune system's reaction to injury or infection. These genes regulate the production of cytokines, chemokines, and other molecules that help control inflammation, and their activity can influence conditions like autoimmune diseases, allergies, and chronic inflammatory disorders.

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Research

5 / 1000+ results

research Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli

September 2018 in “Fertility and Sterility”

This study observed that inflammatory stimuli significantly altered gene expression in rat theca-interstitial cells, affecting pathways related to growth and androgen production, which are central features of polycystic ovary syndrome.

research Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract

22 citations , August 2009 in “Evidence-based Complementary and Alternative Medicine”

This study found that a composition including Serenoa repens extract and anti-inflammatory agents effectively suppressed inflammation-related gene expression in a keratinocyte model, suggesting a potential dual strategy for treating androgenetic alopecia.

research Transcriptomic crossroads: Decoding genes and pathways that connect alopecia areata with chronic inflammatory skin disorders

May 2026 in “JID Innovations”

This study found a significant overlap between gene expression signatures of alopecia areata and certain chronic inflammatory skin disorders, suggesting shared biological processes may drive their co-occurrence and providing a foundation for future research into distinct comorbid subtypes.

research Randomized clinical trial of astaxanthin supplement on serum inflammatory markers and ER stress‐apoptosis gene expression in PBMCs of women with PCOS

19 citations , July 2024 in “Journal of Cellular and Molecular Medicine”

In this study, women with PCOS who took 12 mg of Astaxanthin daily for 8 weeks showed a reduction in certain inflammatory markers and apoptosis-related genes, suggesting potential benefits for managing PCOS, though effects on symptoms like BMI and hirsutism were not significant.

research Dihydrotestosterone, and Not Testosterone, Enhances the LPS-Induced Inflammatory Cytokine Gene Expression in Human Adipocytes

7 citations , April 2023 in “Biomedicines”

This study found that sex hormones, specifically non-aromatizable androgens like DHT and A/T, significantly increase inflammatory cytokine expression in human adipocytes when stimulated by LPS.

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Community Join

5 / 316 results

community Rosemary Oil for inflammatory hairloss? Recommendations?

5 upvotes 1 year ago

A user with seborrheic dermatitis and traction alopecia is seeking alternatives to minoxidil for hair loss, considering rosemary oil for its anti-inflammatory properties. They express concerns about potential side effects and effectiveness of various treatments, including rosemary oil, caffeine, and Redensyl.

community Hairloss Treatment - General health and efficacy-conscious stack overview

1 year ago

The conversation discusses managing hair loss and seborrheic dermatitis with treatments like minoxidil, finasteride, and saw palmetto, emphasizing the importance of scalp health and DHT reduction. The user shares personal experiences and suggests a balanced approach, combining topical treatments and lifestyle changes for effective hair regrowth.

community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 2 years ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Do you think people of previous generations had better hair? What changed?

2171 upvotes 1 year ago

Hair loss is less common now due to accessible treatments like finasteride, minoxidil, and hair transplants. Improved hair care, skincare, and lifestyle changes contribute to people looking younger today.

community What are all of the lifestyle factors that can speed up MPB?

34 upvotes 2 years ago

Genetics mainly cause hair loss, but diet, stress, smoking, and alcohol can worsen it. Treatments include finasteride, minoxidil, and lifestyle changes like a healthy diet and avoiding caffeine.

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Learn

7 / 801 results

learn Lavender

plant and natural oil with antimicrobial and some anti-androgenic effects

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Melatonin

hormone commonly taken for sleep aid has some topical benefits for hair

learn GHK-Cu

a copper peptide showing promise in both regrowth and reversing gray hair

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is one small unblinded pilot study in pattern hair loss, so scalp use is off-label and experimental.

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Experts

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

Clinics

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All 68 clinic results →

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Jane Genesi