Extended Theory of Selective Photothermolysis: A New Recipe for Hair Removal?

    December 2001 in “ Lasers in Surgery and Medicine
    Edward V. Ross
    Image of study
    TLDR Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.
    In the 2001 paper by E. Vic Ross, the extended theory of selective photothermolysis was discussed, suggesting that the pulse-widths used in laser hair removal (LHR) might be too short and should be closer to half a second for better efficacy and skin cooling. The paper reviewed the biology of hair follicles, emphasizing the targeting of the bulge area where stem cells responsible for hair regeneration are located. It was noted that permanent hair reduction is difficult due to the resilience of these stem cells, and that lower power densities could still achieve stem cell death. The study concluded that while temporary growth delay is achievable, permanent hair removal is challenging. The theory supports the use of low power density for hair removal, particularly in darker skin, but further research is needed to confirm if the in-vitro results translate to consistent hair reduction and to establish reliable parameters for permanent follicle destruction.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 153 results

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 3 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Why is Kevin Mann (Haircafe) Hated?

      in Chat  62 upvotes 1 year ago
      Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 2 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 2 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

    Related Research

    1 / 1 results