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Glossary Dystrophic Hairs

hairs damaged or weakened by underlying scalp conditions

Dystrophic hairs are hairs that have been damaged or weakened, often due to underlying conditions such as alopecia areata or other scalp disorders. These hairs typically appear thin, fragile, and may break easily, reflecting a disruption in the normal hair growth cycle. For professionals, the presence of dystrophic hairs can be a diagnostic clue indicating an active disease process affecting the hair follicles.

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Research

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research Patients with profuse hair shedding may reveal anagen hair dystrophy: a diagnostic clue of alopecia areata incognita

31 citations , October 2010 in “Journal of the European Academy of Dermatology and Venereology”

The authors concluded that some patients clinically diagnosed with telogen effluvium may actually have alopecia areata incognita, suggested by the presence of dystrophic hairs and development of alopecia patches.

research Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion?

18 citations , August 2008 in “Journal of Investigative Dermatology”

17-β estradiol and prednisolone may speed up hair regrowth after chemotherapy.

research 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa

November 2024 in “Journal of Investigative Dermatology”

Scalp hair follicle cells help protect and heal skin in certain skin conditions.

research A childhood case of trichotillomania associated with body dysmorphic disorder and stigmatization due to outstanding red hair

1 citations , January 2013 in “International Journal of Trichology”

A girl with red hair developed hair-pulling and body image disorders after being bullied for her hair color.

research Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice

3 citations , January 2021 in “Veterinary dermatology”

This study describes a rare form of congenital alopecia in domestic short hair cats, characterized by hair shaft defects and follicular dystrophy similar to those seen in certain mutant mouse strains.

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Community Join

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community Hair Loss Ruins Your Mind: 10x rate of BDD. PF S is not real

in Research/Science 39 upvotes 7 months ago

Hair loss is linked to a higher rate of body dysmorphic disorder (BDD), OCD, and depression. Finasteride and dutasteride are not linked to increased suicidal risk, though some users report mental health side effects.

community What is up with all these body dysmorphic posts lately?

in Chat 49 upvotes 1 year ago

The conversation discusses concerns about body dysmorphia related to hair loss, with some users expressing frustration over posts claiming treatments like finasteride and dutasteride are ineffective or harmful despite minimal hair loss. It emphasizes the importance of early treatment with medications like finasteride and minoxidil for those experiencing hair loss.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community Hair Loss "a matter of survival" in South Korea

335 upvotes 8 months ago

South Korea's president is advocating for hereditary hair loss to be covered by national health insurance due to its impact on mental health and daily functioning. The discussion highlights the societal pressure in South Korea regarding appearance and the potential benefits of treating hair loss to improve mental health.

community Hair Loss Causes Depression. Not Finasteride.

187 upvotes 7 months ago

Finasteride and Dutasteride do not cause depression or mood disorders; hair loss itself may be a more significant factor. Some users experience side effects from Finasteride, but it is generally well-tolerated.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

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