Use of Contact Immunotherapy in the Treatment of Skin Diseases Other than Alopecia Areata

    September 2022 in “ Dermatology and therapy
    Kun-Wei Lai, Tsen‐Fang Tsai
    Image of study
    TLDR Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
    The document reviews the application of contact immunotherapy, particularly with agents such as DNCB, DPCP, and SADBE, for treating a variety of skin conditions other than alopecia areata. It presents case reports and uncontrolled studies that suggest potential benefits in treating diseases like Merkel cell carcinoma, mycosis fungoides, atopic dermatitis, lichen nitidus, parapsoriasis, prurigo nodularis, systemic lupus erythematosus (SLE), and vitiligo. However, the evidence is limited, and there is a need for more controlled studies to establish efficacy and safety. The review also discusses the adverse effects and safety concerns associated with these treatments, including rare events and the mutagenic potential of DNCB. Despite these concerns, contact immunotherapy remains a cost-effective and convenient option, especially in developing countries and for patients who cannot use conventional therapies. The document emphasizes the need for further research to optimize treatment regimens and to better understand the mechanisms of action of contact immunotherapy. No new studies with human participants or animals were conducted by the authors of the article.
    Discuss this study in the Community →

    Research cited in this study

    19 / 19 results

    Related Community Posts Join

    6 / 344 results

      community No results with medications, now in contact with restoration clinic. Looking for advice on options - including facial hair.

      in Transplants  3 upvotes 8 months ago
      The individual has experienced no hair regrowth from using minoxidil and finasteride and is considering a hair restoration clinic's options, including PRP and nano follicle hair replacement, as well as a potential beard transplant. They are seeking advice on whether to pursue PRP, timing for hair replacement surgery, and experiences with beard transplants.

      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 7 months ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community shampoo nizoral 1% information

      in Ketoconazole  3 upvotes 1 year ago
      User has itching, dandruff, and scalp issues, considering Nizoral 1% shampoo for treatment. Nizoral's effectiveness for hair loss is uncertain due to limited research, short contact time, and concentration differences.

      community GT20029 Anageninc Market Availability

      in Research/Science  164 upvotes 1 year ago
      The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

    Related Research

    1 / 1 results