Diphencyprone Induced Vitiligo: A Case Report

January 2012 in “ Case reports in medicine ”

Mohammad Ali Nilforoushzadeh, Gelavizh Keshtmand, Fariba Jaffary, Abbas Kheirkhah

diphencyprone alopecia areata vitiligo DCP

Studysummary This report describes two cases where patients developed vitiligo as a side effect of diphencyprone treatment for alopecia areata, highlighting the need to inform patients about this potential adverse effect.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

This case report described two patients who developed vitiligo after being treated with diphencyprone (DPCP) for alopecia areata (AA). A 37-year-old man and a 42-year-old woman, both with no personal or family history of vitiligo, experienced vitiligo patches distant from the DPCP application sites. The male patient showed a positive patch test, suggesting DPCP's direct role in causing vitiligo. The report emphasized the unpredictability of vitiligo development with DPCP treatment and the importance of informing patients about this potential adverse effect. Despite the successful regrowth of hair, the persistence of depigmentation led to the discontinuation of DPCP therapy.

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research Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata

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research Alopecia Areata: Diagnosis and Management

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research Vitiligo Complicating Diphencyprone Sensitization Therapy for Alopecia Universalis

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