Acne Exacerbation After Tofacitinib Treatment for Alopecia Areata

    October 2021 in “ Dermatology Reports ”
    Sawsan A Alharthi, Mohammed G. Turkmani, Mohammed Al Jasser
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    TLDR Tofacitinib, a hair regrowth treatment, may worsen acne.
    The paper discusses a case of a 28-year-old male with a 10-year history of alopecia totalis (AT) who was successfully treated with tofacitinib, a Janus kinase (JAK) inhibitor. The treatment showed promising results for hair regrowth. However, four months after the initiation of the AT treatment, the patient's facial acne significantly worsened. This suggests that acne exacerbation could be a potential side effect of JAK inhibitors, which are relatively new treatments for dermatological conditions like moderate to severe forms of alopecia areata (AA). The authors call for larger studies to further investigate the link between acne exacerbation and the use of JAK inhibitors.
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      Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

      in Research  865 upvotes 9 months ago
      The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 9 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 3 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Topical solution recommendation

      in Treatment  1 upvotes 2 days ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Topical solution recommendation

      in Product  1 upvotes 3 days ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

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