Pathobiology of the Hairless Phenotype: Dysregulation of Hair Follicle Apoptosis and Topobiology During the Initiation of Follicle Cycling

    March 1998 in “ Journal of Dermatological Science ”
    Andrey A. Panteleyev, Natalia V. Botchkareva, Carina van der Veen, Angela M. Christiano, Ralf Paus
    TLDR Improper regulation of hair follicle processes causes hairlessness.
    The document titled "Pathobiology of the hairless phenotype: Dysregulation of hair follicle apoptosis and topobiology during the initiation of follicle cycling" from 1998 discussed the mechanisms underlying the hairless phenotype. The study focused on the dysregulation of hair follicle apoptosis and topobiology, which are critical during the initiation of follicle cycling. The researchers identified that improper regulation of these processes led to the hairless condition, providing insights into the biological pathways involved in hair growth and loss. This research contributed to the understanding of hair follicle biology and potential therapeutic targets for hair loss conditions.
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