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    Glossary Hairless Gene

    gene regulating hair growth, mutations cause permanent hair loss

    The Hairless Gene, often abbreviated as HR gene, is a gene that plays a crucial role in the regulation of hair growth and development. Mutations in this gene can lead to conditions such as congenital atrichia, where individuals are born with hair that is subsequently lost and not regrown, resulting in permanent hairlessness. This gene is essential for the normal cycling of hair follicles and the maintenance of hair.

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    Research 10 of 1000+

    1. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    2. The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation American Journal Of Pathology · 1999 · 166 citations
    3. Atrichia Caused by Mutations in the Vitamin D Receptor Gene is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene 2001 · 139 citations
    4. Molecular and functional aspects of the hairless (<i>hr</i>) gene in laboratory rodents and humans Experimental Dermatology · 1998 · 126 citations
    5. A Missense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia in a Family of Irish Travellers The American Journal of Human Genetics · 1998 · 83 citations
    6. A novel missense mutation (C622G) in the zinc‐finger domain of the human hairless gene associated with congenital atrichia with papular lesions Experimental Dermatology · 2000 · 47 citations
    7. A Homozygous Nonsense Mutation in the Zinc-Finger Domain of the Human Hairless Gene Underlies Congenital Atrichia Journal of Investigative Dermatology · 1999 · 37 citations
    8. A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family British Journal of Dermatology · 2000 · 36 citations
    9. Compound Heterozygous Mutations in the Hairless Gene in Atrichia with Papular Lesions Journal of Investigative Dermatology · 2003 · 23 citations
    10. Atrichia with papular lesions resulting from a novel homozygous missense mutation in the hairless gene Clinical and Experimental Dermatology · 2003 · 20 citations
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    Community 10 of 228

    1. Hairloss Treatment - General health and efficacy-conscious stack overview Reddit · 10 Oct 2024
    2. I (diffuse thinner) would genuinely prefer having the Generic MPB hairloss Reddit · 3 Apr 2025
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    6. Creatine and Hairloss (experiment) Reddit · 16 May 2025
    7. My Idea for a possible new hairloss treatment Reddit · 9 Jan 2020
    8. Is there strong correlation with region specific hairloss? Reddit · 22 Sept 2026
    9. Questions about a year of hairloss Reddit · 21 Aug 2024
    10. How to recover from creatine hairloss? Reddit · 20 Dec 2021
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