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GlossaryEDAR gene

provides instructions for a protein crucial in hair development

The EDAR gene provides instructions for making a protein that is crucial for the development of hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which affects these structures, resulting in sparse hair, missing teeth, and reduced ability to sweat.

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A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

research A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

89 citations, August 2008 in “Human genetics”

The EDAR gene greatly affects hair thickness in Asian populations.

research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations, April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

research EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

12 citations, December 2020 in “Archives animal breeding/Archiv für Tierzucht”

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

98 citations, June 2008 in “Human mutation”

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Hair Shaft Structures in EDAR Induced Ectodermal Dysplasia

research Hair Shaft Structures in EDAR Induced Ectodermal Dysplasia

5 citations, September 2015 in “BMC Medical Genetics”

The EDAR gene mutation leads to thinner and more deformed hair shafts.

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