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    Glossary EDAR gene

    provides instructions for a protein crucial in hair development

    The EDAR gene provides instructions for making a protein that is crucial for the development of hair, teeth, and sweat glands. Mutations in this gene can lead to conditions like hypohidrotic ectodermal dysplasia, which affects these structures, resulting in sparse hair, missing teeth, and reduced ability to sweat.

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    Research 10 of 385

    1. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia Human genetics · 2008 · 89 citations
    2. Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats Animals · 2023 · 1 citations
    3. Mutational spectrum of EDA, EDAR, EDARADD, and WNT10A genes in the largest cohort of Russian patients with hypohidrotic ectodermal dysplasia Orphanet Journal of Rare Diseases · 2026
    4. EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes 2020 · 12 citations
    5. Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form Human mutation · 2008 · 98 citations
    6. Generation of Cashmere Goats Carrying an <i>EDAR</i> Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing International Journal of Biological Sciences · 2018 · 33 citations
    7. Novel missense mutation in the EDA gene in a family affected by oligodontia 2016 · 12 citations
    8. Hair shaft structures in EDAR induced ectodermal dysplasia BMC Medical Genetics · 2015 · 5 citations
    9. Advances in the genetic understanding of hypohidrotic ectodermal dysplasia Expert opinion on orphan drugs · 2017 · 1 citations
    10. Divergent genetic mechanism leads to spiny hair in rodents bioRxiv (Cold Spring Harbor Laboratory) · 2018
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