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GlossaryEctodysplasin A Receptor

protein crucial for hair, teeth, and gland development

The Ectodysplasin A Receptor (EDAR) is a protein that plays a crucial role in the development of hair, teeth, and certain glands. Mutations in the EDAR gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

98 citations, June 2008 in “Human mutation”

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

research Ectodysplasin-A2 Induces Dickkopf 1 Expression in Human Balding Dermal Papilla Cells Overexpressing the Ectodysplasin A2 Receptor

4 citations, July 2020 in “Biochemical and Biophysical Research Communications”

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

research Ectodysplasin A (EDA) Signaling: From Skin Appendage to Multiple Diseases

6 citations, August 2022 in “International Journal of Molecular Sciences”

EDA signaling is linked to skin disorders, various cancers, and liver disease.

A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

research A Replication Study Confirmed the EDAR Gene to Be a Major Contributor to Population Differentiation Regarding Head Hair Thickness in Asia

89 citations, August 2008 in “Human genetics”

The EDAR gene greatly affects hair thickness in Asian populations.

EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

research EDA and EDAR Expression at Different Stages of Hair Follicle Development in Cashmere Goats and Effects on Expression of Related Genes

12 citations, December 2020 in “Archives animal breeding/Archiv für Tierzucht”

EDA and EDAR are important for hair follicle development in cashmere goats and affect other related genes.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.