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    Glossary Ectodysplasin A Receptor

    protein crucial for hair, teeth, and gland development

    The Ectodysplasin A Receptor (EDAR) is a protein that plays a crucial role in the development of hair, teeth, and certain glands. Mutations in the EDAR gene can lead to conditions like hypohidrotic ectodermal dysplasia, which is characterized by sparse hair, missing teeth, and reduced ability to sweat.

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    1. Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form Human mutation · 2008 · 98 citations
    2. Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness Human Genetics · 2009 · 42 citations
    3. Ectodysplasin-A2 induces dickkopf 1 expression in human balding dermal papilla cells overexpressing the ectodysplasin A2 receptor Biochemical and Biophysical Research Communications · 2020 · 4 citations
    4. Increased expression of Ectodysplasin A2 Receptor EDA2R is the most remarkable and ubiquitous aging-related transcriptional hallmark Research Square (Research Square) · 2021 · 3 citations
    5. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    6. A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia Human genetics · 2008 · 89 citations
    7. Epidermal patterning and induction of different hair types during mouse embryonic development Birth defects research · 2009 · 81 citations
    8. Transcriptome Reveals Long Non-coding RNAs and mRNAs Involved in Primary Wool Follicle Induction in Carpet Sheep Fetal Skin Frontiers in physiology · 2018 · 37 citations
    9. p53‐dependent transcriptional regulation of EDA2R and its involvement in chemotherapy‐induced hair loss FEBS Letters · 2010 · 37 citations
    10. Genetic and molecular aspects of androgenetic alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018 · 24 citations
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