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    Glossary Epidermal Growth Factor Receptor

    protein on cell surfaces aiding growth and division

    The Epidermal Growth Factor Receptor (EGFR) is a protein found on the surface of cells that helps them grow and divide. It is crucial in regulating cell growth, survival, and differentiation. When EGFR is mutated or overexpressed, it can lead to uncontrolled cell proliferation, which is a common feature in various cancers.

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    1. Epidermal Growth Factor
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    Research 10 of 1000+

    1. Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure. The EMBO Journal · 1995 · 252 citations
    2. Follicular and epidermal alterations in patients treated with ZD1839 (Iressa), an inhibitor of the epidermal growth factor receptor 2002 · 169 citations
    3. Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors European journal of cancer · 2007 · 138 citations
    4. Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. PubMed · 1997 · 107 citations
    5. The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) syndrome British Journal of Dermatology · 2006 · 90 citations
    6. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    7. Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management Dermatology research and practice · 2014 · 68 citations
    8. 2,3,7,8‐Tetrachlorodibenzo‐<i>p</i>‐dioxin causes an increase in protein kinases growth hepatic associated with epidermal factor receptor in the plasma membrane Journal of Biochemical Toxicology · 1988 · 60 citations
    9. Safety Profile of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors: A Disproportionality Analysis of FDA Adverse Event Reporting System Scientific Reports · 2020 · 58 citations
    10. Nonscarring inflammatory alopecia associated with the epidermal growth factor receptor inhibitor gefitinib Journal of the American Academy of Dermatology · 2006 · 57 citations
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    Community 3 of 9

    1. Does applying Epidermal Growth Factor (EGF) make a difference in hair growth? Reddit · 21 Nov 2022
    2. Scalp slapping to increase blood flow? Reddit · 6 Jun 2024
    3. Comprehensive Microneedling Guide Reddit · 19 Aug 2022
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